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diagnosis algorithm classification lymphoma management workup anemia apml bandemia causes cbc chronic comparison differentiation diffuse disorders hemolytic leukemia lymphadenopathy lymphocytic
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involvement Differential ... • Other hematologic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Biopsy • Non-Hodgkin's ... Biopsy • Hodgkin's ... Lymphadenopathy #LAD ... Algorithm #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... lymphocyte > 5000/microL ... PML leukemia, Hodgkin ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... Depletion Non-Hodgkin ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Consider sickle cell ... nucleotidase deficiency, lead ... (oroya fever), babesia ... Algorithm #workup #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Autoantibodies: • WAIHA • CAD ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... compounds, alcohol, lead ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
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