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diagnosis differential algorithm anemia mcv atlas bloodcell classification cobalamin deficiency elevatedmcv macrocytic macrocytosis management microscopy morphology nomenclature nutrition rbc red
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Framework by MCV Microcytic ... Folate deficiency, B12 ... Orotic aciduria, Drugs ... (e.g., hydroxyurea ... Differential #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • Drugs ... Increased Requirement (e.g ... Liver Disease #Macrocytic ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • B12 ... methotrexate) • Drugs ... anti-HLA antibodies Drugs ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... (>100 fL) • B12 ... Deficiency • Drugs ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... RBC: Vitamin B12 ... Chemotherapy (e.g ... disorders, Oxidative drugs ... differential #diagnosis #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... • Common Causes ... dietary intake (e.g ... : • Worsening macrocytic ... , can consider IM
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