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diagnosis differential elevatedmcv macrocytosis mcv microcytic workup atlas classification cobalamin deficiency management mentzerindex microscopy morphology nomenclature nutrition pancytopenia rbc rdw
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Framework by MCV Microcytic ... Infections Macrocytic ... Folate deficiency, B12 ... Orotic aciduria, Drugs ... Differential #Diagnosis #hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... • Alcohol • Drugs ... MatthewHoMD #Macrocytic ... #hematology #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... 95 (or 100) is macrocytic ... (EPO), iron or B12 ... #Workup #Hematology ... #Microcytic #Macrocytic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Blood Smear • Drugs ... Oval Macrocytes ... Liver Disease #Macrocytic ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... disorders, Oxidative drugs ... Diseases #Red #BloodCell
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... methotrexate) • Drugs ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... #Microcytic #Anemia ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... (>100 fL) • B12 ... Deficiency • Drugs ... #Causes #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... corpuscular volume into microcytic ... MCV 80-100 fl) & macrocytic ... Pancytopenia is a hematologic ... These causes could
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... : • Worsening macrocytic ... anemia, yellow ... wt loss • If anemia ... , can consider IM
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