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differential hematology algorithm classification macrocytic mcv rbc acidosis aplastic bloodcell cobalamin elevatedmcv elevation fat fatrbc lactate lactic macrocytosis microscopy mnemonic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Framework by MCV Microcytic ... , B12 deficiency ... Orotic aciduria, Drugs ... (e.g., hydroxyurea
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... RBC: Vitamin B12 ... disorders, Oxidative drugs ... #differential #diagnosis ... hematology #microscopy #atlas
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Blood Smear • Drugs ... • Dietary Deficiency ... Increased Requirement (e.g
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Deficiency •
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... Chronic Disease (e.g ... (>100 fL) • B12 ... • Drugs • Reticulocytosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... : • Worsening macrocytic ... , can consider IM ... #diagnosis #management
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
of Macrocytic Anemia ... Folate (Fetus) and B12 ... Deficiency - Impairs ... #Macrocytic #Anemia ... #Differential #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... , GATA2 deficiency ... , CTLA4 deficiency ... oncology #hematology #diagnosis ... #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
circulation If drugs ... malignancy, or thiamine deficiency ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... : Drugs and Toxins
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