11 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... = nonspecific (nausea ... , ↑Tbili/Dbili/AP ... iMedEducation #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... specificity to elevated ALP ... Cholestatic Injury: • ALP ... both are normal, ALP ... hemolysis) • ALP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... Intestine - Other causes ... #Phosphatase #ALP
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... of Pregnancy (AFLP ... Hemolysis, Elevated Liver ... child * Severe cases ... TTPHUS #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Algorithm Severe ALT ... • Pregnancy - AFLP ... HELLP Moderate ALT ... Diagnosis #Algorithm #Causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... in 1923 Low ALP ... 1948 by Rathbun ALP ... synthesized in: liver ... Phosphatase: • Other causes
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... exchange 2) Fatty liver ... coagulation defects and liver ... TTPHUS #HELLP #AFLP
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... Nucleotidase • ALT ... obstruction • ALP ... or higher • Liver
Here another case. On the PA-film a mass is seen that fills the aortopulmonary window. Final
Here another case ... mass is seen that fills ... Lateral #APWindow #AP
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
• Person who lives ... and no apparent focus ... Liver enlargement ... involvement, such as liver ... impairment (AST or ALT