18 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia ... #pathophysiology ... #geriatrics #diagnosis
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... early stages of infection ... Diagnosis: MRI ... Findings: • Rule out infectious ... The clinical syndrome
Causes of Sore Throat / Rhinorrhea - Differential Diagnosis Algorithm
Common viral pathogens: Rhinovirus, Coronavirus, Influenza virus,
/ Rhinorrhea - Differential ... Diagnosis Algorithm ... Cytomegalovirus, HIV ... Acute Head Cold Syndrome ... Tracheobronchitis • Acute Infectious
Infectious Causes of Adrenal Insufficiency
Anatomical distribution of vessels to the adrenal makes the gland prone to
are at greatest risk ... Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... Insufficiency #AI #differential ... #diagnosis #endocrinology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... sites) ↑ Risk ... ♀, ↑Age, ESRD Pathophysiology ... → Calculate 4T score ... • If 4T score
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... Herpes zoster - HIV ... injury • DVT (Risks ... #diagnosis #lower
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Statins), ETOH Infection ... (Viral- HIV, Influenza ... Dermatomyositis) AKI - Pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Attempt if high risk ... initiation • Differential ... Diagnosis: Infection
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Diagnosis Framework ... • Acquired Risk ... • Nephrotic Syndrome ... Venous #Arterial #pathophysiology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Diagnosis Framework ... Pneumonia: • Risk ... #differential #