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hematology infectiousdiseases management oncology aids differential hiv listeria listeriosis microbiology monocytogenes neurology treatment algorithm associated autoimmune cancer cns differentiation disorder
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... : >3 symptoms, or ... : Infection (sepsis ... fluid overload, PCC ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... activity • ↓ LAP Score ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... pathogens, including PML ... cells per μL • Diagnosis ... disorientation, memory ... #differential #diagnosis
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
beta-hemolytic, Non-spore-forming ... Risk Factors: ... Diagnosis: ... Gastroenteritis) • PCR ... / CT if focal symptoms
Listeriosis Summary - Listeria Monocytogenes Pathogen: Listeria Monocytogenes - Gram-positive rod, Aerobic, facultative anaerobe, motile, beta-hemolytic, Non-spore-forming Risk
beta-hemolytic, Non-spore-forming ... Risk Factors: ... Diagnosis: ... Gastroenteritis) • PCR ... / CT if focal symptoms
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV dementia ... early stages of infection ... • Depressive symptoms ... Diagnosis: MRI ... Findings: • Rule out infectious
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... carries a variable risk ... • Parvovirus infection ... and reducing the risk ... Myelodysplastic #Syndromes #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... Thrombosis highest risk ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
acute respiratory symptoms ... • Rheumatologic ... MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... transplantation • MCC
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
collectively have a high symptom ... disease-associated symptoms ... median age at diagnosis ... may result in an infection ... #algorithm #hematology
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