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differential management signs symptoms rheumatology dermatology neurology cryoglobulinemia treatment workup abscess acromegaly agraphia alexia algorithm arteritis ascorbicacid calcium centralretinalartery classification
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
semiology of Cutaneous Vasculitis ... Identification of causes ... (5%): PAN > GPA ... signs #lesions #diagnosis ... #clinical #manifestations
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... ANCA (C-ANCA): GPA ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
cryoglobulinemia vasculitis ... - Diagnosis, causes ... Clinical manifestations ... infection - GCs ... Cryoglobulinemic #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Differential Diagnosis ... : Vasculitis: ... dermatology #rash #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... Diagnosis = clinical ... w/differential diagnosis ... = vasculitis vs ... identifies 85 to 95% of cases
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Labs/Diagnosis: ... Cryoglobulins #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... • Other rare causes ... Overproduction #diagnosis ... signs #symptoms #endocrinology ... #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Pathogenesis and Clinical ... periumbilical region), nausea ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Evaluation 1) Clinical ... clues - Is the ... check the urine Ca ... #differential #diagnosis ... #endocrinology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
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