13 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
made in the liver ... sinusoid (hepatic ... or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Complications • Ascites ... Esophageal Varices • Hepatic ... • Spontaneous Bacterial ... Complications #diagnosis ... management #summary #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Acute fatty liver ... Infections - Bacterial ... #Causes #diagnosis ... #differential #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... - Differential Diagnosis ... - Massive liver ... failure - Hepatic ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... portal HTN: • Ascites ... INR, bilirubin, albumin ... #causes #hepatology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Spontaneous Bacterial ... and Management Ascites ... Presentation in septic ... response Give IV albumin ... dysfunction or liver
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
or venipuncture sites ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiency • Liver ... gangrenosum • Bacterial ... #Differential #Diagnosis ... #hematology #rheumatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Syndrome, Ischemic Liver ... intravascular coagulation ... pathophysiology #hematology ... #differential #diagnosis