16 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
made in the liver ... or not by the liver ... sinusoid with (ie Portal ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... HTN: ascites (SAAG ... HTN: • Ascites ... INR, bilirubin, albumin ... #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... - Differential Diagnosis ... - Massive liver ... syndrome) - Portal ... #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Portal hypertension ... Liver disease ... - Acute fatty liver ... #Causes #diagnosis ... #differential #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential Diagnosis ... Hypertension - Hepatic ... disease • Acute liver ... Hypertension - Post-Hepatic ... #Algorithm #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
or venipuncture sites ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Production: • Albumin ... • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Peritonitis (SBP) - Diagnosis ... and Management Ascites ... Presentation in septic ... response Give IV albumin ... dysfunction or liver
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Laboratory Findings in Hepatic ... Hypoalbuminemia - Decreased albumin ... #LiverFailure #Hepatic ... #Hepatology #Laboratory ... #Diagnosis #Testing
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Prolonged Activated Partial ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential #hematology