10 results
differential causes hepatology abnormal albumin aptt gradient interpretation prolonged pt serum analysis arterial bleeding bruising chemistry dic embolism fluid hemostasis
Deciphering the SAAG - Serum to Ascites Albumin Gradient Ascites is either made in the liver sinusoid
Deciphering the SAAG ... either made in the liver ... or not by the liver ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Hepatic congestionl ... Liver disease ... - Acute fatty liver ... #Causes #diagnosis ... #differential #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... (SAAG>I.I), esophageal ... portal HTN: • Ascites ... #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Differential Diagnosis ... - Massive liver ... failure - Hepatic ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... or venipuncture sites ... DIC • Severe Liver ... #diagnosis #causes ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Disseminated intravascular ... Prolonged #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... hemorrhage • Disseminated ... #differential #hematology ... #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Syndrome, Ischemic Liver ... thrombocytopenia - Disseminated ... intravascular coagulation ... pathophysiology #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #Hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... Acquired: • Heparin ... failure, disseminated ... #Hematology
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