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differential hepatology causes albumin algorithm gradient interpretation management serum abnormal abscess analysis aptt arterial bleeding bruising chemistry children dermatology dic
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Portal hypertension ... Liver disease ... - Acute fatty liver ... Portal vein occlusion ... #Causes #diagnosis
Deciphering the SAAG - Serum to Ascites Albumin Gradient Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... sinusoid with (ie Portal ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... HTN: ascites (SAAG ... HTN: • Ascites ... sarcoidosis) • Liver ... #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Differential Diagnosis ... - Massive liver ... syndrome) - Portal ... #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Differential Diagnosis ... Hypertension - Hepatic ... disease • Acute liver ... Hypertension - Post-Hepatic ... #Algorithm #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
or venipuncture sites ... DIC • Severe Liver ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... replaced by non-hepatic ... disease: > 2 • NASH ... #chemistry #diagnosis ... #differential #Hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Prolonged Activated Partial ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... disease: > 2 • NASH ... #differential #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Syndrome, Ischemic Liver ... intravascular coagulation ... pathophysiology #hematology ... #differential #diagnosis
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