18 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiency • Liver ... Associated - SLE ... fever • Drug reactions ... #hematology #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... test, ANA (e.g., SLE ... Causes #Workup #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... Leucopenia/lymphopenia, Thrombocytopenia ... signs #symptoms #diagnosis ... #rheumatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... AIHA, Transfusion reactions ... Defects, Drugs, Liver ... - Peripheral Blood ... #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... - Thalassemia, Liver ... Thrombotic idiopathic thrombocytopenia ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Neurological 12% - Thrombocytopenia ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... purpura & severe thrombocytopenia ... eruptions, diarrhea, liver ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... purpura & severe thrombocytopenia ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE ... • Liver function ... #Management #Hematology ... #Rheumatology
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Characteristic Rash ... • Fomites • Live ... Umbilification - Rash ... Polymerase chain reaction ... #MPOX #Diagnosis