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differential management anemia algorithm causes hemolytic workup leukemia blood comparison monoclonal rbc syndrome thrombocytopenia aflp atlas chronic classification clinical dermatomyositis
Map of proliferative blood disorders. By Ariella Coler-Reilly @ariellastudies #Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Increased red cell ... Increased red cell ... Causes #Workup #Hematology ... #Diagnosis *
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... fragmentation hemolysis ... organ or stem cell ... #differential #diagnosis ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... Hemoglobinopathies (e.g. sickle cell ... #differential #diagnosis ... #hematology #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... - Differential Diagnosis ... • Sickle cell ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Phosphorus CLL ... ) CLL Symptoms: ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Asplenism, Severe hemolytic ... Sideroblastic anemia, Hemolytic ... Thalassemia, Sickle cell ... Inclusions #Bodies #diagnosis ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Diagnosis: • ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects: Sickle cell ... #Differential #Diagnosis ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Consider sickle cell ... #Differential #Diagnosis ... Algorithm #workup #hematology
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