29 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Algorithm Reactive ... : - Systemic Inflammatory ... • Systemic ... #Hematology #Oncology
Indolent Systemic Mastocytosis (ISM)

 • Introduction and Diagnosis
 • Diagnostic Algorithm and Risk Stratification
 • Symptoms
Indolent Systemic ... Algorithm and Risk ... and Symptom Management ... @ZhuoerXie #Systemic ... #SM #Indolent #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... joints Nervous system ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... - Most common systemic ... years - Rare in adults ... #Rheumatology # ... Peds #Pediatrics
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
guidelines General - Systemic ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... solid cancers • Systemic ... management #treatment #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... (eg, skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
both children and adults ... the onset of the systemic ... symptoms - ... bleeding, or other symptoms ... #MPOX #Diagnosis