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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... Secondary: CTD: SLE ... #skin #dermatology ... #rheumatology # ... differential #diagnosis
Cryoglobulinemia Vasculitis
#rheumatology #diagnosis #signs
Cryoglobulinemia Vasculitis ... #rheumatology ... #diagnosis #signs
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... #differential #diagnosis ... #rheumatology
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Splenomegaly - CTD (SLE ... Associated - SLE ... #hematology #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... especially in the skin ... HenochSchonleinPurpura #HSP #Diagnosis ... #Rheumatology # ... Peds #Pediatrics
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
semiology of Cutaneous Vasculitis ... disease (10%) : SLE ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Drug-induced SLE ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Associations #diseases #diagnosis ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Differential Diagnosis ... purpura: strong sign ... , and SLE) • Urinalysis ... #rheumatology #