37 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... #Diagnosis #hematology ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Sequestration Disordered ... Platelet Function ... • Steroids • Vasculitis ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... Inflammatory Conditions: Rheumatologic ... , Vasculitides, ... #hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Diagnosis Framework ... #skin #dermatology ... #rheumatology # ... differential #diagnosis
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... #disorders #hematology ... #hemepath #differential ... #diagnosis #Aggregometry
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Connective tissue disorders ... #Diagnosis #Algorithm ... #hematology #platelets
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... without platelet ... MYH9-Related Disorder ... comparison #table #differential ... #diagnosis #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
inherited bleeding disorder ... bruising • Skin ... Laboratory • Normal platelet ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... #Disorders #Differential ... #Diagnosis #Causes ... #Workup #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis ... #rashes #differential ... #diagnosis #rheumatology