17 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis ... manifestations - Skin ... infection - GCs ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... Urticarial/LCV) - Cryoglobulinemic ... polyangiitis - EGPA - GPA ... #skin #dermatology ... differential #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
expression - Age: GCA ... skin lesions ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
(5%): PAN > GPA ... hemopathies (4%) • Cryoglobulinemia ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin ... and branches • GCA ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... Labs/Diagnosis: ... - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... : Vasculitis: ... purpura • Mixed cryoglobulinemia ... #dermatology #rash ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... /HSP • Cryoglobulinemia ... - GPA - EGPA ... #hematology #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... / ANCA + MPO) Cryoglobulinemic ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... (Cryoglobulinemic ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology