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algorithm aki differential microscopy nephritic syndrome urine classification injury kidney kidneyinjury proteinuria renal workup ain atlas blood crisis diseases glomerulonephritis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient have glomerular ... hematuria (RBC casts ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology ... #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome == Nephrotic Syndrome == Onset - Insidious Edema - ++++ Blood
Red blood cell casts ... Red blood cell casts ... edgarvlermamd - Nephrology ... #Comparison #Table ... #Nephrology #Diagnosis
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... suggestive of nephrotic ... Urine #Microscopy #nephrology ... interpretation #diagnosis
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
INTRINSIC: - Glomerular ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... treating underlying cause
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Interstitial Nephritis ... sterile pyuria, WBC casts ... proteinuria, granular casts ... AIN #Algorithm #nephrology ... #diagnosis
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
- TTP/HUS • Glomerular ... tubular necrosis (causes ... interstitial nephritis ... Classification #diagnosis ... #nephrology
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Simplified Approach to Acute ... Urinary obstruction, Nephrotoxic ... PROBLEM ~80% of AKI cases ... for WBCs, RBCs, casts ... #nephrology
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