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differential aki algorithm table casts causes kidneyinjury glomerular urine acutekidneyinjury atlas classification clinicopathology compared dermatology diuresis diuretics encephalopathy erythemas excretion
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
of Glomerular Diseases ... proliferation • Breaks in ... differential #spectrum #diagnosis ... #nephrology #nephritic ... #nephrotic #comparison
Acute Kidney Injury (AKI) - Common Patterns on Urinalysis - Prerenal - ATN - AIN -
Acute Kidney Injury ... - AIN - UTI ... AKI #Urinalysis #diagnosis ... #table #comparison ... #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... #nephrology #pathology ... #comparison #table ... #diagnosis #microscopy
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and Disease ... acute tubular necrosis ... Advanced kidney disease ... #Differential #Microscopy ... #Diagnosis #Nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach to Acute ... Interstitial Nephritis ... eosinophiluria, microscopic ... MatthewHoMD #Acute ... #nephrology #diagnosis
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
tubular cells - Acute ... Red cell casts - Diagnostic ... brown cast” - Necrotic ... protein indicating acute ... #nephrology #casts
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
causes: sepsis, meds ... interstitial nephritis ... (AIN) Postrenal ... Classification #diagnosis ... #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #nephrology #interpretation ... #diagnosis
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
CHF, cirrhosis, nephrotic ... Pain. ... Nausea, Pulmonary Diseases ... , CNS Disease, Meds ... #nephrology #sodium
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... • Primary GNs: Disease ... Interstitial Nephritis ... (AIN) • Drugs ... #nephrology
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