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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... other elements Nephritic ... differential #spectrum #diagnosis ... #nephrology #nephritic ... #nephrotic #comparison
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... - Diagnostic approach ... > 500 mg/d • Nephritic ... #Nephritis #diagnosis ... #nephrology #biopsy
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... • Lupus ISN/RPS ... Haemolytic-uraemic syndrome Nephrotic ... #diseases #nephrology ... #table #diagnosis
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... #differential #diagnosis ... #management #nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... nephritis (LN) ... in 10 to 40% of SLE ... #Nephritis #Management ... #rheumatology #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... #Differential #Diagnosis ... #Nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
- TTP/HUS • Glomerular ... causes: sepsis, meds ... Acute interstitial nephritis ... Classification #diagnosis ... #nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... Erythematosus (SLE ... nephritis, NPSLE ... #sle #comparison ... #rheumatology #diagnosis