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diagnosis treatment rheumatology differential druginduced nephrology neurology signs comparison complications dil erythematosus hyperkalemia k manifestations mucocutaneous myelitis palsy pathophysiology potassium
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... 40, F:M 9:1 • Clinical ... Usual therapeutic management
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Langerhan cells ... hair follicles -> causes ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... tissue: Epithelioid cells ... renal failure Clinical ... skin (16-32%): lupus ... Sarcoidosis #Diagnosis #Management
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... - Atypical Clinical ... systemic signs (rash ... Imaging (if atypical symptoms ... CNS inflammatory cause
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... Immobilization - Crush ... Dermatomyositis Clinical ... : • Triad of symptoms
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... diagnosis #treatment #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Lysis (TLS, rhabdo/crush ... tourniquet / IVF line draw ... only if no clear cause ... and Elimination (see ... Drives K+ into cells
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... • Infectious causes ... Disorders: - SLE ... Myelitis #diagnosis #management
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