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diagnosis management rheumatology signs differential treatment erythematosus pathophysiology systemic druginduced nephrology neurology vasculitis acute avascularnecrosis centralretinalartery classification comparison complications crao
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... Discontinuation of causal ... 40, F:M 9:1 • Clinical
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Langerhan cells ... hair follicles -> causes ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... , oral ulcers, Lupus ... Positive in 60-80% of cases
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... #SLE #systemic ... erythematosus #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... : • Symptoms limited ... : Drug induced SLE
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
tissue: Epithelioid cells ... renal failure Clinical ... Features: • Many symptoms ... patients have no symptoms ... skin (16-32%): lupus
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... - Atypical Clinical ... systemic signs (rash ... Imaging (if atypical symptoms ... CNS inflammatory cause
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
(28%) • Skin rash ... elevation • Nausea ... decrease (<200 cells ... 14%), in which case ... • New onset SLE
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... GCA, SLE, GPA) - ... retinal edema caused ... Retina • Ganglion cells ... diagnosis #signs #symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Immobilization - Crush ... Dermatomyositis Clinical ... : • Triad of symptoms ... kidney tubular cells
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