12 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... patches on the skin ... #diagnosis #signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... The signs and symptoms ... ▪ “Rash” (75% ... resembling rashes caused
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... symptoms by days ... Causes: - Idiopathic
Manifestations of Anaphylaxis by Body System

Dermatologic/mucosal

 - Eyes: periorbital swelling/erythema, injected conjunctiva, tears

 - Oral mucosa:
tongue and lips - Skin ... : urticarial rash ... Gastrointestinal - Nausea ... Diagnosis #Allergy #Signs ... #Symptoms #Anaphylaxis
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... pathophysiology #genetics #endocrinology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Thickening of skin ... hyperthyroidism #causes ... #differential #endocrinology ... #signs #symptoms
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
fatigue Heat Rash ... blisters on the skin ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... differential #diagnosis #causes
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Clinical Features 1) Skin ... easily bruisable skin ... darkening of the skin ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign