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diagnosis differential dermatology sle vasculitis antinxp2 antinxp2dm arteritis autoimmune classification complications dermatomyositis erythematosus gca giantcell manifestations mucocutaneous myopathy myositis oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis #signs ... #symptoms #complications
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... symptoms by days ... Causes: - Idiopathic ... ’s syndrome - Lupus
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... nodes: 13-15%, skin ... (16-32%): lupus ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... required due to skip ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused
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