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diagnosis differential rheumatology lupus neurology treatment druginduced summary vasculitis anaplasma anesthesia anesthesiology bells checklist classification cns comparison complications embolism embolus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... constitutional symptoms ... Manifestations: Malar rash
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... #diagnosis #signs ... #symptoms #complications
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... and symptoms: ... shaking chills • Rash ... ), cough (30% cases
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar rash ... versus DIL • ... Positive in 60-80% of cases ... Usual therapeutic management
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
fatigue Heat Rash ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... differential #diagnosis #causes
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
in Anaesthesia Causes ... Signs: hypotension ... decreased ETCO2 Symptoms ... • Petechial rash ... mainstay of initial management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... Discontinuation of causal ... diagnosis #treatment #management
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Immobilization, Crush ... Dermatomyositis) AKI - Pathophysiology ... See updated ... #Summary #causes
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... Maculopapular rash ... influenzae Symptoms ... Acute meningeal signs ... • Uveitis • Rash
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Diagnosis and Management ... ophthalmoplegia), systemic signs ... (rash, swelling ... Imaging (if atypical symptoms ... CNS inflammatory cause
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