61 results
Nikolsky’s Sign - Febrile & Positive Nikolsky’s Sign: Patients in this group have the potential to
Nikolsky’s Sign ... - Febrile & Positive ... Nikolsky’s Sign ... sick (Fever + Rash ... Derm #Nikolsky #Sign
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Fever, malaise • Rash ... Early Latent: • Positive ... Late Latent: • Positive ... Stages #symptoms #signs
Clarke's Test (Patellar Grind Test)

Indicates Patellofemoral dysfunction.
 - Patient with knee in extension. Push posterior on
Push posterior on ... - Positive sign
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... in 60-80% of cases
Labyrinthitis 
Vestibular neuritis + unilateral hearing loss = Labyrinthitis 
1) Vertigo (severe) 
2) Gait instability 
3)
instability 3) Nausea ... fixation) • Positive ... Diagnosis #Symptoms #Signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... - Anti-ENA - Positive ... - Anti-dsDNA - Positive ... in 60-80% of cases ... Anti-histone - Positive
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Management Caused ... Symptoms and Signs ... myorhythmia OR • PAS-positive ... Two different positive ... specimen OR • One positive
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
within morulae Signs ... shaking chills • Rash ... is rare (< 10% cases ... ), cough (30% cases
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
is thought to cause ... the Positive Symptoms ... is thought to cause ... diagnosis #symptoms #signs ... #psychiatry #positive
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
from a seated position ... This is a case of ... 1) heliotrope rash ... , 2) shawl sign,