25 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... marrow leading to a more ... ) CLL Symptoms: ... mosquito bites CLL ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... or don’t work properly ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... lymphocytes, smudge cells ... Transformation to large cell ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... lymphadenopathy more ... common - T Cell ... ~10% - B-Cell ... Responsive to Treatment
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
lesions +1 or more ... marrow plasma cell ... , B and T cell lymphoproliferative ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... More common in severe ... #oncology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
orientation): • More ... increased IgG4+ cells ... but rituximab more ... management #phenotypes #workup ... #treatment #rheumatology
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... support - Call ... and Survey 4) Workup ... Management #Summary #criticalcare ... #treatment #workup