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pharmacology dm2 diagnosis differential medications nephrology sglt2 summary table acidosis algorithm aniongap canagliflozin comparison dapagliflozin diabeticketoacidosis disorders diuresis diuretics dka
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
gliflozin): • Empagliflozin ... loss (~2-3kg) • Empagliflozin ... • Euglycemic diabetic ... #Summary #DM2 #diabetes ... #endocrinology
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Diabetic ketoacidosis ... (DKA) - caused ... seen with SGLT inhibitors ... Glucosuria causes ... diagnosis #management #endocrinology
SGLT2 inhibitors, also called gliflozins, are a class of medications that alter essential physiology of the
SGLT2 inhibitors ... that modulate sodium ... treatment of type II diabetes ... (Farxiga®) and empagliflozin ... , #empagliflozin
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... out of cells may cause ... to a day after ketosis ... pathophysiology #endocrinology ... #diabetes
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... class of anti-diabetic ... kidney), which causes ... Medications #DM2 #Diabetes ... #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... Mechanisms of Action: Inhibits ... not definitively cause ... #Summary #DM2 #diabetes ... #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... Sulfonylurea, TZD, DPP-4 inhibitor ... α-glucosidase inhibitor ... comparison #table #endocrinology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Causes of High-anion ... Ketoacidosis: Diabetic ... Calcineurin inhibitors ... potential bicarbonate: ketosis ... with ketone excretion
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperparathyroidism • Diabetic ... drugs • ACE inhibitors ... Diagnosis #Algorithm #endocrinology ... #causes
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Nephrogenic diabetes ... insipidus • Kidney stones ... caused by Ca2+ ... Lithium-induced nephrogenic diabetes ... DDAVP) • Central diabetes
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