15 results
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Hypovolemic Shock ... #Shock #Pathophysiology ... differential #diagnosis #algorithm ... #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
rash; symptoms of shock ... within GI and URT causes ... Maternal viremia causes ... > Inflammation causes ... peds #pediatrics #pathophysiology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Diagnosis Framework Pre-Renal ... , Distributive Shock ... , HRS, Hypercalcemia ... Diagnosis #nephrology #causes ... #algorithm
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... Diagnosis Algorithm ... Bacteremia Septic Shock ... Differential #Diagnosis #Algorithm ... #causes
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Caused by splanchnic ... Pathophysiology: ... Exclude other AKI causes ... Classification: ... essential in all cases
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Negative IF): • PR3 ... differential #diagnosis #algorithm
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... velocity) - ↑ PR ... ACCP Cardiology PRN ... #Pharmacology #Classification ... #Classes #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... dysfunction (16%) • Shock ... - Reduction of pro ... Treat primary cause ... Coagulation #diagnosis #causes
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Pathophysiology ... • 49 million cases ... COMMON CAUSES + ... • Symptoms: Fever ... all suspected cases
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Presentation: • Classic ... malignancy Pathophysiology ... GH + IGF-1 → multisystemic ... or refractory cases ... Endocrinology #Treatment #Pathophysiology