1802 results
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... with Castleman's disease ... Mixed variant • Multicentric ... Autoimmune diseases ... #Castlemans #Disease
Unicentric Castleman Disease (UCD) vs Multicentric Castleman Disease (MCD) - Comparison Table

Unicentric Castleman Disease (UCD):
 •
Unicentric Castleman Disease ... (UCD) vs Multicentric ... Castleman Disease ... after surgery Multicentric ... #Unicentric #Multicentric
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation
Kaposi sarcoma (KS):
 • Target organs: Ubiquitous (cutaneous and mucosal
HHV8/KSHV-reIated diseases ... chain: - HHV8+ Multicentric ... Castleman Disease ... Fremont #HHV8 #diseases
CASTLEMAN DISEASE
Disorder of the immune system with excessive production of IL-6

Castleman’s disease is a rare, heterogeneous
CASTLEMAN DISEASE ... Castleman’s disease ... (UCD) • Multicentric ... Castleman disease ... Multicentric Castleman
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
evidence of KSHV-multicentric ... Castleman disease ... Infectious Diseases
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Treating HHV-8 Diseases—Kaposi ... Lymphoma (PEL), Multicentric ... Castleman’s Disease ... disseminated cutaneous disease ... lifethreatening disease
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
considered a variant of multicentric ... Castleman disease ... infection, rickettsial disease ... , Lyme disease,
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... glomerulonephritis - Berger disease ... Minimal change disease ... #Glomerular #Diseases
General overview of lung diseases. 

#diagnosis #causes #lung #disease #restrictive #obstructive #pulmonary #respiratory #pearls #ddxof
overview of lung diseases ... #causes #lung #disease
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... lymphomas, Hodgkin disease ... Chronic inflammatory diseases ... , IgG4-related disease ... inflammatory bowel diseases