6 results
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... pathogens Bacterial ... activation -> Complement ... #pathophysiology
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... eradication of pathogen ... Pathogen cleared ... activation of complement ... #Gonorrhea #Pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... (bacteria, viruses ... Opsonization: Abs coat pathogens ... Neutralization: Abs bind to pathogen ... Humoral #Immunity #pathophysiology
Diarrhea Workup and Management Algorithm in Transplant Patients
First Tier Microbiologic-Testing:
1. C. difficile PCR (Stool)
2. CMV qPCR
Diarrhea Workup ... and Management Algorithm ... Bacterial culture ... range of enteric pathogens ... #Diarrhea #Workup
Solid Organ Transplant - Diarrhea - Diagnostic and Workup Algorithm
1st Tier Microbiologic Testing: CDiff (stool), CMV
Diagnostic and Workup ... Algorithm 1st Tier ... pathogens 2nd Tier ... SolidOrgan #Diagnosis #Workup ... #Algorithm
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... NETs), cytokines, complement ... • Pathogens: ... Gram-positive/-negative bacteria