418 results
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
TERT promoter mutations ... Thyroid #Carcinoma #Pathology
Langerhans cell histiocytosis presenting as a solitary jaw cyst. Classic reniform nuclei, prominent eosinophils, S100+, CD1A+,
exclusive) MAP2K1 mutations ... histiocytosis #Jaw #Pathology
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
sections • KIT mutation ... mastocytosis #hemepath #pathology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
nonspecific - Missense mutations ... Leukemia #hemepath #pathology
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
& BRAF V600e mutations ... Thyroid #Cancer #Pathology
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
defect - Mutations ... ATPase - AEI mutations ... defect - ENaC mutation ... - SCNN mutation ... HTN (WNKI and 4 mutations
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
Each individual mutation ... However, when these mutations
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... due to ALS - Mutations
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Atlas #Microscopy #Pathology ... Robbins & Cotran Pathologic
Polycythemia vera, Essential thrombocythemia, Primary myelofibrosis Diagnosis Algorithm
 • Polycythemia vera → Blood JAK2 mutation screening
vera → Blood JAK2 mutation ... thrombocythemia → Blood mutation ... marrow biopsy with mutation