45 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
- Autoimmune: thyroid ... variable degree of weakness ... Limb- proximal weakness ... Differential DX: - Thyroid ... Severe bulbar weakness
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
or respiratory weakness ... treatment Of ocular ... mild to moderate weakness ... or generalized weakness ... crisis, treatment
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
irregularities • Weakness ... ↑ AST/ALT • Treatment ... tenderness Treatment ... #differential #endocrinology ... #signs #symptoms
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Hyperthyroidism – symptoms ... Symptoms: Weight ... Stiffness, Muscle weakness ... dermopathy, Thyroid ... Signs #Diagnosis #Endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
thyroglobulin, Thyroid ... thyroglobulin, thyroid ... etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... NMJ disorder (Myasthenia ... Vasculitis OVERLAP: • Thyroid ... #Generalized #Weakness
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... Myalgia, Muscle weakness ... Features #Signs #Symptoms ... #PhysicalExam #Endocrinology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Eaton Syndrome, Myasthenia ... dermatomyositis, Thyroid ... Neuromuscular #Weakness
REBEL Review 71: Treatment of Thyroid Storm 

Propranolol 
Esmolol 
Propylthiouracil (PTU) 
Methimazole 
Saturated Solution of Potassium
REBEL Review 71: Treatment ... of Thyroid Storm ... Hydrocortisone #endocrinology ... table #management #treatment
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... s disease, the thyroid ... ‘Leakage’ symptoms ... Eventually thyroid ... Hashitoxicosis #Hashimotos #Endocrinology