16 results
diagnosis algorithm causes anemia bleeding bruising hemolytic oncology thrombocytopenia aggregometry classification comparison extravascular gap globulin hemepath hemostasis hodgkins inherited intravascular
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Defects Bernard-Soulier ... Syndrome • Defect ... MYH9-Related Disorder ... #table #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... with or without platelet ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #nonpalpable #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
lymphoproliferative disorders ... Intrinsic RBC Defects ... thalassemias), Membrane defects ... Extravascular #Causes #differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Diagnosis #Algorithm #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
< 1800/uL, • platelet ... /uL Initial Workup ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology ... #workup
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... with qualitative defects ... #disorders #hematology ... #hemepath #differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Quantitative Defect ... Sequestration Disordered ... Platelet Function ... - Qualitative Defect ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... #Disorders #Differential ... Diagnosis #Causes #Workup ... #hematology
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... - Differential ... Qualitative Defects ... #Disorders #Differential ... #Diagnosis #hematology
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