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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
disorders. ... #Algorithm #classification ... #disorders #leukemia ... #hematology #oncology ... #CLL #AML #Map
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... , Sudan Black, Auer ... @AmyChung #Blood ... #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... • (Peripheral eosinophilia ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... #Hematology #Oncology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... (neutrophils, eosinophils ... disorders: > 100,000 ... Neutrophil bands ... part automated differential
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... the total white blood ... Myeloproliferative Disorders ... (CML) - associated ... Diagnosis #causes #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Treated Like Acute Leukemias ... #Classification ... #pathophysiology ... #Hematology #Diagnosis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... with sparing of hands ... multiple myeloma or AL ... be seen after blood ... comparison #table #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... count with differential ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... #hematology #oncology