15 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... , Sudan Black, Auer ... rod • Lymphoid ... #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... Neutrophils • Immature/Myeloblasts ... Age: 50-60 • Auer ... - infiltrates (anemia ... #Leukemia #Hematology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... , monoblast, & lymphoid ... (neutrophils, eosinophils ... disorders: > 100,000 ... part automated differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... #differential # ... neutrophil #WBC #CBC #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Treated Like Acute Leukemias ... Lymphoproliferative #Disorders ... #Classification ... pathophysiology #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm Blood ... • RBC Membrane Disorder ... #Classification ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... marrow biopsy - if blood ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
or lymphoid malignancy ... - Monoclonal - Lymphoid ... younger pts) Differential ... sensitize red blood ... #hematology #diagnosis