13 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Diagnosis Algorithm ... Signs of anemia ... peripheral smear ... Diagnosis #Algorithm
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Diagnosis Algorithm ... Normal Blood Smear ... • Pernicious Anemia ... #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Diagnosis Algorithm ... • Anemia of Chronic ... Non-lmmune #Anemia ... #Diagnosis #Algorithm
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
approximately 5-10% of peripheral ... on the left Myeloblast ... (Normal) Differential ... diagnosis #neutrophil ... #WBC #CBC #hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... She was diagnosed ... blood smear showed ... #Clinical #Path ... #Smear #Microscopy
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... proportion of the red blood ... leads to anemia ... Normal range11.5
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Defects: Sickle cell anemia ... Dehydrogenase ↑ - Peripheral ... Blood Smearabnormal ... #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Peripheral Smear ... : Acute blood loss ... hemolysis, deficiency anemia ... #Diagnosis #Algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... dyserythropoietic anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... plateletcount), peripheral ... blood smear, HIV ... changes), high MCV anemia