6 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... hemolytic anemia ... hemolytic anemia ... #Morphology #differential ... diagnosis #hematology #microscopy
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... #Hemolytic #Anemia
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... Membrane): - Autoimmune ... 3) Internal (RBC ... Smear ↑ abnormal
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
disorder or lymphoid ... - Monoclonal - Lymphoid ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... nodosum • Immune hemolytic ... anemia • Pain ... platelets - WBC ... Immunohistochemical studies (to differentiate
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
No hemolytic anemia ... Investigations: • CBC ... a chest film; blood-smear ... dipstick test, microscopic ... Fever #Travel #Differential