14 results
diagnosis hematology differential algorithm oncology management neurology systemic anemia generalized leukemia pruritus rheumatology agglutinin apex cerebritis chronic cll cns cold
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anemia Clinical ... and petechiae Causes ... • ↓ WBC • ↓ ... result from low blood ... Anemia #oncology #hematology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm Hypertension - BP > 140/90 (>130/80 for DM) Hypertensive urgency
Secondary Causes ... based on repeat clinic ... visits, Ambulatory blood ... 3+) Consider secondary ... #Nephrology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
/ Systemic == Blood ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... APS), Secondary
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Chediak-Higashi syndrome ... drug reactions - Secondary ... including white blood ... cell aplasia DOI ... #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm Blood ... Myelodisplastic syndrome ... #Pruritus #secondary ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... smear - RBC agglutination ... sensitize red blood
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... • Richter’s Syndrome
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