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diagnosis differential algorithm syndrome management urine nephrotic renal urology workup casts nephritic neurology proteinuria treatment acute aki blood classification clinical
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
: 3 or more RBC/ ... : - RBC casts ... - Dysmorphic RBC ... and SMA - Can cause ... #urology #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... of UTI, urine WBCs ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
of Macroscopic Hematuria ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... #IM #Urology #Hematuria
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... Comparison #Algorithm #Nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sterile pyuria, WBC ... casts, eosinophiluria ... , microscopic hematuria ... proteinuria, granular casts ... AIN #Algorithm #nephrology
Causes of Dysuria - Differential Diagnosis Algorithm Pyuria - Leukocytes on Dipstick/Microscopy - Bacteriuria & Hematuria -
Causes of Dysuria ... Bacteriuria & Hematuria ... Pyelonephritis - WBC ... Infection/Cystitis - WBC ... Bacteriuria & No Hematuria
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Dysmorphic RBCs and/or RBC ... casts) - Isolated ... Hematuria with ... Diagnosis #Algorithm #Causes
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
hematuria. ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... white blood cell (WBC ... Mature WBC: 80- ... LEUCOCYTOSIS WBC ... the underlying cause
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... urine sediment - WBC ... /RBC casts ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
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