13 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... #Diseases #Nephritic ... #Proteinuria #Nephrology ... #Diagnosis
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... EM) Haematuria/nephritis ... polyangiitis #glomerular ... #diseases #nephrology ... comparison #table #diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... Dysmorphic RBCs and/or RBC ... • Thin GBM disease ... • Pauci-immune disease
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Red cell casts - Diagnostic ... of glomerular disease ... brown cast” - Necrotic ... #Atlas #key #diagnosis ... #nephrology #casts
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... casts → Diagnostic ... disease Renal ... causes #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... urine sediment - WBC ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #nephrology #interpretation ... #diagnosis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... (Dense deposit disease ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24- ... #testing #workup ... #diagnosis #glomerulonephritis ... #nephrotic #nephritic ... #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
disease 1) 24- ... #glomerular #disease ... #workup #diagnosis ... initial #testing #nephrology ... #nephrotic #nephritis