12 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... anemia, Thalassemias ... Hypophostphatemia Laboratory ... Peripheral Blood Smear ... Diagnosis #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
Causes of Anemia ... , Spur cell anemia ... anemia, Hemolysis ... Kumfer @AnnKumfer #Anemia ... #Cirrhosis #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... #hemolytic #anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... result in severe anemia ... anemia Indirect ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... • Anemia • Aplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... cells can indicate disease ... • Neutropenia, anemia ... #oncology #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... lysis → severe hemolytic ... anemia, jaundice ... TREATMENT: ​• Acute
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... anemia • Pain ... Hodgkin Lymphoma Workup ... #oncology #management