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algorithm anemia management classification mcv oncology approach autoimmune deficiency hemodialysis hemolytic hodgkins lymphoma mds morphologic myelodysplasia myelodysplastic nephrology pruritus rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
> normocytic, ↑ ... • IgG type ± C3d ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #treatment #rheumatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
inflammation) • Iron ... Normocytic ( ... , CKD • Hemolytic ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Acute Bleed - Normocytic ... Disease • Marrow ... #Causes #Hematology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... #Deficiency #differential ... #diagnosis #causes ... #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
disorders • Celiac disease ... effect following treatment ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... 80 - 96 fL - "Normocytic ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... Platelet Disorders • Nutritional ... rings of excess iron ... blood count with differential ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
primary lesions - differential ... diagnosis: • ... pruritus • Hematologic ... pruritus (Iron ... #Pruritus #Treatment
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