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management algorithm anemia classification oncology rheumatology approach arthritis autoimmune ckd deficiency disorders hemodialysis hemolytic hodgkins laboratory lymphoma mcv mds morphologic
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... > normocytic, ↑ ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #treatment #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Acute Bleed - Normocytic ... Disease • Marrow ... #Causes #Hematology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... #Deficiency #differential ... #diagnosis #causes ... #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
disorders • Celiac disease ... effect following treatment ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... 80 - 96 fL - "Normocytic ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... (CVID, WAS), (neurologic ... #Diagnosis #Causes ... #Workup #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... ferritin level, and iron ... (to support a diagnosis ... #diagnosis #testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... Platelet Disorders • Nutritional ... rings of excess iron ... blood count with differential ... #hematology #oncology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Infectious causes ... antibodies • Nutritional ... Transverse Myelitis Treatment ... #management #neurology ... #differential
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... levels of GAD, an antibody ... that works against ... #neurology
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