14 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Metastatic Disease ... #Workup #Differential ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Metastatic Disease ... #Workup #Differential ... #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Diseases: • GATA2 ... deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Diagnosis #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Iron deficiency ... chronic kidney disease ... Underproduction #Algorithm #hematology ... #diagnosis #differential ... #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Acute Bleed - Normocytic ... Disease • Marrow ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... inflammation) • Iron ... Normocytic ( ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... Loss (without anaemia ... #Deficiency #differential ... #diagnosis #causes ... #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... disorders • Celiac disease ... effect following treatment ... malignancy • Iron ... deficiency anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... Microcytic" • Iron ... 80 - 96 fL - "Normocytic ... morphologic #mcv #differential ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... ITP, unexplained pancytopenia ... #Workup #hematology