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diagnosis oncology sle anemia classification eosinophils erythematosus hes hypereosinophilia intravascular systemic vasculitis acquired activation algorithm antinxp2 antinxp2dm aplastic bandemia behcet
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... Diagnosis and Treatment ... #HES #Hematology ... #eosinophilia # ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... Secondary Causes ... #diagnosis #hematology ... #differential # ... management #eosinophils
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Amyloidosis • Eosinophilic ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #skin #rashes #differential ... #diagnosis #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... antiphospholipid syndrome ... S - Systemic Lupus ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
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