26 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Treatment Algorithm ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... glucocorticoid treatment ... may be indicated ... #Differential # ... diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... clinical manifestations ... Hypereosinophilia #Syndrome ... #diagnosis #hematology ... #differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
significant: > 10% Band ... Band neutrophils ... to right with bands ... appreciate the value of band ... neutrophil #WBC #CBC #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5. ... • Hypoplastic MDS ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5 ... • Hypoplastic MDS ... #Hematology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... with sparing of hands ... the mainstay of treatment ... #Scleroderma #Differential ... comparison #table #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
eruption that may ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology