23 results
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... eosinophils, & basophils ... Mature WBC: 80- ... part automated differential ... NEUTROPHILS #WCC #BASOPHILS
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... platelets, persistent WBC ... after initial Rx), basophilia ... #Leukocytosis #Differential ... Algorithm #hematology #WBC
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Eosinophils 3) Basophils ... Nikolsky #Algorithm #Differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Neutrophil (Normal) Differential ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... of disease and complications ... This leads to RBC ... SickleCell #Disease #Pathophysiology ... #Complications
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Volume (MCV) - Differential ... - Fe/TlBC, MCV/RBC ... <13, +/- basophilic ... inclusions in RBC ... #elevatedMCV #Differential
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... ischemia-induced RBC ... hemolysis) • RBC ... #Hyperkalemia #Differential ... potassium #high #pathophysiology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... thalassemia, S Lepore • Basophilic ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Hemolytic #Anemia #Differential
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
The vitamin B12 (Cbl ... HC, releasing Cbl ... The IF-Cbl complex ... VitaminB12 #deficiency #Differential ... Causes #Diagnosis #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... bile ducts Differential