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hemolytic classification coagulation abnormal agglutinin algorithm atlas cold disseminated hodgkins key lymphoma morphology prolonged pt rbc thromboticthrombocytopenicpurpura treatment ttp workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... #Hemolytic #Intravascular ... #Extravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... and Intravascular ... Hemolysis - Differential ... Differential #Diagnosis ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... #Anemia #Differential ... classification #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Disseminated intravascular ... coagulopathy (DIC ... #Atlas #key #diagnosis ... #differential # ... hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... reflection of intravascular ... from ischemia WBC ... count and differential ... #Workup #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Severe Liver Disease ... INR < 2.3 - APTT ... #Disseminated #Intravascular ... #management #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... pts) Differential ... the RBCs causing intravascular ... #hemolytic #anemia ... #hematology #diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Disseminated intravascular ... coagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... number of sites of disease ... classification #hematology ... #oncology #management
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